• Human Mesothelin/MSLN protein (Recombinant) (C-His & Avi) {Biotin} (STJP002185)
  • Human Mesothelin/MSLN protein (Recombinant) (C-His & Avi) {Biotin} (STJP002185)
  • Human Mesothelin/MSLN protein (Recombinant) (C-His & Avi) {Biotin} (STJP002185)

Human Mesothelin/MSLN protein (Recombinant) (C-His & Avi) {Biotin} (STJP002185)

SKU:
STJP002185-100

€709.38
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Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Mesothelin/MSLN-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Immobilized Biotinylated Human MSLN, His Tag at 0.5 Mu g/mL (100 Mu L/Well). Dose response curve for Anti-MSLN Ab with the EC50 of 3.7 ng/mL determined by ELISA.
Gene Symbol: MSLN
Gene ID: 10232
Uniprot ID: MSLN_HUMAN
Immunogen Region: Glu296-Gly580
Immunogen: Biotinylated Recombinant Human Mesothelin Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Glu296-Gly580) of Human Mesothelin fused with His tag and Avi tag at the C-terminal.
Post Translational Modifications Both MPF and the cleaved form of mesothelin are N-glycosylated. Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.
Function Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
Protein Name Mesothelin
Cak1 Antigen
Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor
Mpf - Mesothelin - Cleaved Form
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Golgi Apparatus
Megakaryocyte-Potentiating Factor: Secreted
Isoform 3: Secreted
Alternative Protein Names Mesothelin protein
Cak1 Antigen protein
Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor protein
Mpf - Mesothelin - Cleaved Form protein
MSLN protein
MPF protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance