| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human LY96-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | LY96 |
| Gene ID: | 23643 |
| Uniprot ID: | LY96_HUMAN |
| Immunogen Region: | Glu17-Asn160 |
| Immunogen: | Homo sapiens (Human) |
| Function | Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS. |
| Protein Name | Lymphocyte Antigen 96Ly-96Esop-1Protein Md-2 |
| Database Links | Reactome: R-HSA-1236974Reactome: R-HSA-140534Reactome: R-HSA-166016Reactome: R-HSA-166058Reactome: R-HSA-166166Reactome: R-HSA-2562578Reactome: R-HSA-5602498Reactome: R-HSA-5603041Reactome: R-HSA-5686938Reactome: R-HSA-936964Reactome: R-HSA-937041Reactome: R-HSA-937072Reactome: R-HSA-9707616Reactome: R-HSA-975163Reactome: R-HSA-9820960Reactome: R-HSA-9824878Reactome: R-HSA-9833110 |
| Cellular Localisation | SecretedExtracellular SpaceRetained In The Extracellular Space At The Cell Surface By Interaction With Tlr4 |
| Alternative Protein Names | Lymphocyte Antigen 96 proteinLy-96 proteinEsop-1 proteinProtein Md-2 proteinLY96 proteinESOP1 proteinMD2 protein |
Information sourced from Uniprot.org
