| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
1.15ng/mL |
| Detection Limit: |
3.12-200ng/mL |
| Short Description: |
This LPCAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
LPCAT1 |
| Gene ID: |
79888 |
| Uniprot ID: |
PCAT1_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Erythrocytes. |
| Post Translational Modifications | |
| Function | Exhibits acyltransferase activity. Exhibits acetyltransferase activity. Activity is calcium-independent. Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. Involved in the regulation of lipid droplet number and size. |
| Protein Name | Lysophosphatidylcholine Acyltransferase 1Lpc Acyltransferase 1Lpcat-1Lysopc Acyltransferase 11-Acylglycerol-3-Phosphate O-Acyltransferase1-Acylglycerophosphocholine O-Acyltransferase1-Alkenylglycerophosphocholine O-Acyltransferase1-Alkylglycerophosphocholine O-AcetyltransferaseAcetyl-Coa -Lyso-Platelet-Activating Factor AcetyltransferaseAcetyl-Coa -Lyso-Paf AcetyltransferaseLyso-Paf AcetyltransferaseLysopafatAcyltransferase-Like 2Phosphonoformate Immuno-Associated Protein 3 |
| Database Links | Reactome: R-HSA-1482788Reactome: R-HSA-1482925Reactome: R-HSA-1483166Reactome: R-HSA-1483191Reactome: R-HSA-6798695 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinGolgi Apparatus MembraneCell MembraneLipid DropletMay Adopt A Monotopic Topology When Embedded In The Lipid Monolayer Of The Lipid DropletWith Both Termini Exposed To The Cytoplasm |
| Alternative ELISA Names | Lysophosphatidylcholine Acyltransferase 1 ELISA kitLpc Acyltransferase 1 ELISA kitLpcat-1 ELISA kitLysopc Acyltransferase 1 ELISA kit1-Acylglycerol-3-Phosphate O-Acyltransferase ELISA kit1-Acylglycerophosphocholine O-Acyltransferase ELISA kit1-Alkenylglycerophosphocholine O-Acyltransferase ELISA kit1-Alkylglycerophosphocholine O-Acetyltransferase ELISA kitAcetyl-Coa -Lyso-Platelet-Activating Factor Acetyltransferase ELISA kitAcetyl-Coa -Lyso-Paf Acetyltransferase ELISA kitLyso-Paf Acetyltransferase ELISA kitLysopafat ELISA kitAcyltransferase-Like 2 ELISA kitPhosphonoformate Immuno-Associated Protein 3 ELISA kitLPCAT1 ELISA kitAYTL2 ELISA kitPFAAP3 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
