Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.117ng/mL |
Detection Limit: |
0.312-20ng/mL |
Short Description: |
This LILRA3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
LILRA3 |
Gene ID: |
11026 |
Uniprot ID: |
LIRA3_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung. |
Post Translational Modifications | N-glycosylation is required for ligand binding. |
Function | Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes. |
Protein Name | Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3Cd85 Antigen-Like Family Member EImmunoglobulin-Like Transcript 6Ilt-6Leukocyte Immunoglobulin-Like Receptor 4Lir-4Monocyte Inhibitory Receptor Hm43/Hm31Cd Antigen Cd85e |
Database Links | Reactome: R-HSA-198933Reactome: R-HSA-6798695 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 ELISA kitCd85 Antigen-Like Family Member E ELISA kitImmunoglobulin-Like Transcript 6 ELISA kitIlt-6 ELISA kitLeukocyte Immunoglobulin-Like Receptor 4 ELISA kitLir-4 ELISA kitMonocyte Inhibitory Receptor Hm43/Hm31 ELISA kitCd Antigen Cd85e ELISA kitLILRA3 ELISA kitILT6 ELISA kitLIR4 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance