• Human LECT1 (Leukocyte Cell Derived Chemotaxin 1) Sandwich ELISA Kit (STJE0010299)

Human LECT1 (Leukocyte Cell Derived Chemotaxin 1) Sandwich ELISA Kit (STJE0010299)

SKU:
STJE0010299

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.051ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This LECT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CNMD
Gene ID: 11061
Uniprot ID: CNMD_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.
Post Translational Modifications After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
Function Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
Protein Name Leukocyte Cell-Derived Chemotaxin 1
Chondromodulin Cleaved Into - Chondrosurfactant Protein
Ch-Sp - Chondromodulin-1
Chondromodulin-I
Chm-I
Database Links
Cellular Localisation Chondromodulin-1: Secreted
Extracellular Space
Extracellular Matrix
Accumulated In The Inter-Territorial Matrix Of Cartilage
Chondrosurfactant Protein: Endomembrane System
Single-Pass Membrane Protein
Alternative ELISA Names Leukocyte Cell-Derived Chemotaxin 1 ELISA kit
Chondromodulin Cleaved Into - Chondrosurfactant Protein ELISA kit
Ch-Sp - Chondromodulin-1 ELISA kit
Chondromodulin-I ELISA kit
Chm-I ELISA kit
CNMD ELISA kit
CHMI ELISA kit
LECT1 ELISA kit
MYETS1 ELISA kit
output

Information sourced from Uniprot.org

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