• Human KNTC1 (Kinetochore-associated protein 1) Sandwich ELISA Kit (STJE0010213)

Human KNTC1 (Kinetochore-associated protein 1) Sandwich ELISA Kit (STJE0010213)

SKU:
STJE0010213

£352.50 - £682.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.056ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This KNTC1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: KNTC1
Gene ID: 9735
Uniprot ID: KNTC1_HUMAN
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity High expression in testis.
Post Translational Modifications
Function Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
Protein Name Kinetochore-Associated Protein 1
Rough Deal Homolog
Hsrod
Rod
Hrod
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-5663220
Reactome: R-HSA-68877
Reactome: R-HSA-9648025
Cellular Localisation Cytoplasm
Nucleus
Chromosome
Centromere
Kinetochore
Cytoskeleton
Spindle
Dynamic Pattern Of Localization During The Cell Cycle
At Interphase
Uniformly Distributed Throughout The Cytoplasm And Nucleus
By Prophase And Until Late Stages Of Prometaphase
A Fraction Of The Total Pool Is Concentrated At Kinetochores
By Metaphase
Detected At Kinetochores
Along Spindle Fibers And Most Prominently At The Poles
By Late Anaphase Until The End Of Telophase
No Longer Detectable On Kinetochores Or Along Spindle Fibers
But Still Present At The Spindle Poles
Alternative ELISA Names Kinetochore-Associated Protein 1 ELISA kit
Rough Deal Homolog ELISA kit
Hsrod ELISA kit
Rod ELISA kit
Hrod ELISA kit
KNTC1 ELISA kit
KIAA0166 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance