| Function | Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury. |
| Protein Name | Kallikrein-8Hk8NeuropsinNpOvasinSerine Protease 19Serine Protease Tadg-14Tumor-Associated Differentially Expressed Gene 14 Protein |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | SecretedCytoplasmShows A Cytoplasmic Distribution In The Keratinocytes |
| Alternative Protein Names | Kallikrein-8 proteinHk8 proteinNeuropsin proteinNp proteinOvasin proteinSerine Protease 19 proteinSerine Protease Tadg-14 proteinTumor-Associated Differentially Expressed Gene 14 Protein proteinKLK8 proteinNRPN proteinPRSS19 proteinTADG14 proteinUNQ283 proteinPRO322 protein |
Information sourced from Uniprot.org
