Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 30pg/mL |
Detection Limit: | 78.1-5000pg/mL |
Short Description: | This KLb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | KLB |
Gene ID: | 152831 |
Uniprot ID: | KLOTB_HUMAN |
Sample Type: | serum, plasma or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | |
Function | Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21. |
Protein Name | Beta-KlothoBklBetaklothoKlotho Beta-Like Protein |
Database Links | Reactome: R-HSA-109704Reactome: R-HSA-1257604Reactome: R-HSA-1307965Reactome: R-HSA-2219530Reactome: R-HSA-5654228Reactome: R-HSA-5654712Reactome: R-HSA-5654719Reactome: R-HSA-5654720Reactome: R-HSA-5654733Reactome: R-HSA-5673001Reactome: R-HSA-6811558 |
Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane Protein |
Alternative ELISA Names | Beta-Klotho ELISA kitBkl ELISA kitBetaklotho ELISA kitKlotho Beta-Like Protein ELISA kitKLB ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance