• Human KCNJ10 (Potassium Inwardly Rectifying Channel Subfamily J, Member 10) Sandwich ELISA Kit Ready-To-Use (STJE0016523)

Human KCNJ10 (Potassium Inwardly Rectifying Channel Subfamily J, Member 10) Sandwich ELISA Kit Ready-To-Use (STJE0016523)

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STJE0016523

€648.13 - €891.88
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.64ng/mL
Detection Limit: 1.56-100ng/mL
Short Description: This KCNJ10 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: KCNJ10
Gene ID: 3766
Uniprot ID: KCJ10_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in kidney (at protein level).
Post Translational Modifications
Function May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules.this process is critical for Na(+) reabsorption at the tubules.
Protein Name Atp-Sensitive Inward Rectifier Potassium Channel 10
Atp-Dependent Inwardly Rectifying Potassium Channel Kir4.1
Inward Rectifier K(+ Channel Kir1.2
Potassium Channel - Inwardly Rectifying Subfamily J Member 10
Database Links Reactome: R-HSA-1296041
Reactome: R-HSA-1296067
Reactome: R-HSA-997272
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
In Kidney Distal Convoluted Tubules
Located In The Basolateral Membrane Where It Colocalizes With Kcnj16
Alternative ELISA Names Atp-Sensitive Inward Rectifier Potassium Channel 10 ELISA kit
Atp-Dependent Inwardly Rectifying Potassium Channel Kir4.1 ELISA kit
Inward Rectifier K(+ Channel Kir1.2 ELISA kit
Potassium Channel - Inwardly Rectifying Subfamily J Member 10 ELISA kit
KCNJ10 ELISA kit
output

Information sourced from Uniprot.org

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