| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.066ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This IRF2BP2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
IRF2BP2 |
| Gene ID: |
359948 |
| Uniprot ID: |
I2BP2_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylation at Ser-360 is required for nuclear targeting. |
| Function | Acts as a transcriptional corepressor in a IRF2-dependent manner.this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation. |
| Protein Name | Interferon Regulatory Factor 2-Binding Protein 2Irf-2-Binding Protein 2Irf-2bp2 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative ELISA Names | Interferon Regulatory Factor 2-Binding Protein 2 ELISA kitIrf-2-Binding Protein 2 ELISA kitIrf-2bp2 ELISA kitIRF2BP2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
