| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
24.6pg/mL |
| Detection Limit: |
78.1-5000pg/mL |
| Short Description: |
This IL5Ra Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
IL5RA |
| Gene ID: |
3568 |
| Uniprot ID: |
IL5RA_HUMAN |
| Sample Type: |
serum, plasma or other biological fluids. |
| Tissue Specificity | Expressed on eosinophils and basophils. |
| Post Translational Modifications | |
| Function | Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway. |
| Protein Name | Interleukin-5 Receptor Subunit AlphaIl-5 Receptor Subunit AlphaIl-5r Subunit AlphaIl-5r-AlphaIl-5raCdw125Cd Antigen Cd125 |
| Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-912526 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | Interleukin-5 Receptor Subunit Alpha ELISA kitIl-5 Receptor Subunit Alpha ELISA kitIl-5r Subunit Alpha ELISA kitIl-5r-Alpha ELISA kitIl-5ra ELISA kitCdw125 ELISA kitCd Antigen Cd125 ELISA kitIL5RA ELISA kitIL5R ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
