| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.43 pg/mL |
| Detection Limit: |
156-100 pg/ml |
| Short Description: |
This IL5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Conjugation: |
Biotin |
| Storage Instruction: |
Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month. |
| Assay Time: |
4 hours |
| Detection: |
Colorimetric |
| Gene Symbol: |
IL5 |
| Gene ID: |
3567 |
| Uniprot ID: |
IL5_HUMAN |
| Sample Type: |
serum, plasma and cell culture supernates |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively. |
| Protein Name | Interleukin-5Il-5B-Cell Differentiation Factor IEosinophil Differentiation FactorT-Cell Replacing FactorTrf |
| Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-912526 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Interleukin-5 ELISA kitIl-5 ELISA kitB-Cell Differentiation Factor I ELISA kitEosinophil Differentiation Factor ELISA kitT-Cell Replacing Factor ELISA kitTrf ELISA kitIL5 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
