| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.127ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This IL22Ra2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
IL22RA2 |
| Gene ID: |
116379 |
| Uniprot ID: |
I22R2_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach. |
| Post Translational Modifications | |
| Function | Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy. |
| Protein Name | Interleukin-22 Receptor Subunit Alpha-2Il-22 Receptor Subunit Alpha-2Il-22r-Alpha-2Il-22ra2Cytokine Receptor Class-Ii Member 10Cytokine Receptor Family 2 Member 10Crf2-10Cytokine Receptor Family Type 2 - Soluble 1Crf2-S1Interleukin-22-Binding ProteinIl-22bpIl22bpZcytor16 |
| Database Links | Reactome: R-HSA-8854691 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Interleukin-22 Receptor Subunit Alpha-2 ELISA kitIl-22 Receptor Subunit Alpha-2 ELISA kitIl-22r-Alpha-2 ELISA kitIl-22ra2 ELISA kitCytokine Receptor Class-Ii Member 10 ELISA kitCytokine Receptor Family 2 Member 10 ELISA kitCrf2-10 ELISA kitCytokine Receptor Family Type 2 - Soluble 1 ELISA kitCrf2-S1 ELISA kitInterleukin-22-Binding Protein ELISA kitIl-22bp ELISA kitIl22bp ELISA kitZcytor16 ELISA kitIL22RA2 ELISA kitUNQ5793 ELISA kitPRO19598 ELISA kitPRO19822 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
