• Human IL12Rb2 (Interleukin 12 Receptor Beta 2) Sandwich ELISA Kit Ready-To-Use (STJE0016158)

Human IL12Rb2 (Interleukin 12 Receptor Beta 2) Sandwich ELISA Kit Ready-To-Use (STJE0016158)

SKU:
STJE0016158

£408.50 - £556.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This IL12Rb2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: IL12RB2
Gene ID: 3595
Uniprot ID: I12R2_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Isoform 2 is expressed at similar levels in both naive and activated T-cells.
Post Translational Modifications On IL12 binding, phosphorylated on C-terminal tyrosine residues by JAK2. Phosphorylation on Tyr-800 is required for STAT4 binding and activation, and for SOCS3 binding.
Function Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Protein Name Interleukin-12 Receptor Subunit Beta-2
Il-12 Receptor Subunit Beta-2
Il-12r Subunit Beta-2
Il-12r-Beta-2
Il-12rb2
Database Links Reactome: R-HSA-8984722
Reactome: R-HSA-9020591
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Interleukin-12 Receptor Subunit Beta-2 ELISA kit
Il-12 Receptor Subunit Beta-2 ELISA kit
Il-12r Subunit Beta-2 ELISA kit
Il-12r-Beta-2 ELISA kit
Il-12rb2 ELISA kit
IL12RB2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance