| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
7.8 pg/mL |
| Detection Limit: |
156-1000 pg/mL |
| Short Description: |
This IL11 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Conjugation: |
Biotin |
| Storage Instruction: |
Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month. |
| Assay Time: |
4 hours |
| Detection: |
Colorimetric |
| Gene Symbol: |
IL11 |
| Gene ID: |
3589 |
| Uniprot ID: |
IL11_HUMAN |
| Sample Type: |
serum, plasma and cell culture supernates |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation. Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling'. |
| Protein Name | Interleukin-11Il-11Adipogenesis Inhibitory FactorAgifOprelvekin |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Interleukin-11 ELISA kitIl-11 ELISA kitAdipogenesis Inhibitory Factor ELISA kitAgif ELISA kitOprelvekin ELISA kitIL11 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
