Human IDH1 protein (Recombinant) (N-His) (STJP003385)

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STJP003385
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IDH1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IDH1
Gene ID: 3417
Uniprot ID: IDHC_HUMAN
Immunogen Region: Met1-Leu414
Immunogen: Homo sapiens (Human)
Function Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency.
Protein Name Isocitrate Dehydrogenase Nadp Cytoplasmic
Idh
Idh1
Cytosolic Nadp-Isocitrate Dehydrogenase
Idpc
Nadp(+-Specific Icdh
Oxalosuccinate Decarboxylase
Database Links Reactome: R-HSA-2978092
Reactome: R-HSA-389542
Reactome: R-HSA-6798695
Reactome: R-HSA-9033241
Reactome: R-HSA-9818025
Cellular Localisation Cytoplasm
Cytosol
Peroxisome
Alternative Protein Names Isocitrate Dehydrogenase Nadp Cytoplasmic protein
Idh protein
Idh1 protein
Cytosolic Nadp-Isocitrate Dehydrogenase protein
Idpc protein
Nadp(+-Specific Icdh protein
Oxalosuccinate Decarboxylase protein
IDH1 protein
PICD protein

Information sourced from Uniprot.org