• Human HTR1A (5-Hydroxytryptamine Receptor 1A) Sandwich ELISA Kit Ready-To-Use (STJE0015979)

Human HTR1A (5-Hydroxytryptamine Receptor 1A) Sandwich ELISA Kit Ready-To-Use (STJE0015979)

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STJE0015979

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.059ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This HTR1A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: HTR1A
Gene ID: 3350
Uniprot ID: 5HT1A_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Detected in lymph nodes, thymus and spleen. Detected in activated T-cells, but not in resting T-cells.
Post Translational Modifications
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Protein Name 5-Hydroxytryptamine Receptor 1a
5-Ht-1a
5-Ht1a
G-21
Serotonin Receptor 1a
Database Links Reactome: R-HSA-390666
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Dendrite
Alternative ELISA Names 5-Hydroxytryptamine Receptor 1a ELISA kit
5-Ht-1a ELISA kit
5-Ht1a ELISA kit
G-21 ELISA kit
Serotonin Receptor 1a ELISA kit
HTR1A ELISA kit
ADRB2RL1 ELISA kit
ADRBRL1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance