• Human HMBS (Hydroxymethylbilane Synthase) Sandwich ELISA Kit Ready-To-Use (STJE0015850)

Human HMBS (Hydroxymethylbilane Synthase) Sandwich ELISA Kit Ready-To-Use (STJE0015850)

SKU:
STJE0015850

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.27ng/mL
Detection Limit: 0.781-50ng/mL
Short Description: This HMBS Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: HMBS
Gene ID: 3145
Uniprot ID: HEM3_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Isoform 1: Is ubiquitously expressed. Isoform 2: Is found only in erythroid cells.
Post Translational Modifications
Function As part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen. Catalysis begins with the assembly of the dipyrromethane cofactor by the apoenzyme from two molecules of porphobilinogen or from preuroporphyrinogen. The covalently linked cofactor acts as a primer, around which the tetrapyrrole product is assembled. In the last step of catalysis, the product, preuroporphyrinogen, is released, leaving the cofactor bound to the holodeaminase intact.
Protein Name Porphobilinogen Deaminase
Pbg-D
Hydroxymethylbilane Synthase
Hmbs
Pre-Uroporphyrinogen Synthase
Database Links Reactome: R-HSA-189451
Cellular Localisation Cytoplasm
Alternative ELISA Names Porphobilinogen Deaminase ELISA kit
Pbg-D ELISA kit
Hydroxymethylbilane Synthase ELISA kit
Hmbs ELISA kit
Pre-Uroporphyrinogen Synthase ELISA kit
HMBS ELISA kit
PBGD ELISA kit
UPS ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance