| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
5.9pg/mL |
| Detection Limit: |
15.6-1000pg/mL |
| Short Description: |
This GZMM Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
GZMM |
| Gene ID: |
3004 |
| Uniprot ID: |
GRAM_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Highly and constitutively expressed in activated natural killer (NK) cells. |
| Post Translational Modifications | |
| Function | Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells. |
| Protein Name | Granzyme MMet-1 Serine ProteaseHu-Met-1Met-AseNatural Killer Cell Granular Protease |
| Database Links | Reactome: R-HSA-173736 |
| Cellular Localisation | SecretedCytoplasmic GranuleGranules Of Large Granular Lymphocytes |
| Alternative ELISA Names | Granzyme M ELISA kitMet-1 Serine Protease ELISA kitHu-Met-1 ELISA kitMet-Ase ELISA kitNatural Killer Cell Granular Protease ELISA kitGZMM ELISA kitMET1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
