• Human GSTA1 protein (Recombinant) (C-His) (STJP001448)

Human GSTA1 protein (Recombinant) (C-His) (STJP001448)

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STJP001448-20

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Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human GSTA1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4, 5% trehalose, mannitol and 0.01% Tween80.
Gene Symbol: GSTA1
Gene ID: 2938
Uniprot ID: GSTA1_HUMAN
Immunogen: Recombinant Human GSTA1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Phe222) of human GSTA1 (Accession #NP_665683.1) fused with a 6Ă—His tag at the C-terminus.
Function Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid.
Protein Name Glutathione S-Transferase A1
13-Hydroperoxyoctadecadienoate Peroxidase
Androst-5-Ene-3 -17-Dione Isomerase
Gst Ha Subunit 1
Gst Class-Alpha Member 1
Gst-Epsilon
Gsta1-1
Gth1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed
Database Links Reactome: R-HSA-156590
Reactome: R-HSA-189483
Reactome: R-HSA-9748787
Reactome: R-HSA-9818027
Cellular Localisation Cytoplasm
Alternative Protein Names Glutathione S-Transferase A1 protein
13-Hydroperoxyoctadecadienoate Peroxidase protein
Androst-5-Ene-3 -17-Dione Isomerase protein
Gst Ha Subunit 1 protein
Gst Class-Alpha Member 1 protein
Gst-Epsilon protein
Gsta1-1 protein
Gth1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed protein
GSTA1 protein

Information sourced from Uniprot.org

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