Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human GSTA1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4, 5% trehalose, mannitol and 0.01% Tween80. |
Gene Symbol: |
GSTA1 |
Gene ID: |
2938 |
Uniprot ID: |
GSTA1_HUMAN |
Immunogen: |
Recombinant Human GSTA1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Phe222) of human GSTA1 (Accession #NP_665683.1) fused with a 6×His tag at the C-terminus. |
Function | Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid. |
Protein Name | Glutathione S-Transferase A113-Hydroperoxyoctadecadienoate PeroxidaseAndrost-5-Ene-3 -17-Dione IsomeraseGst Ha Subunit 1Gst Class-Alpha Member 1Gst-EpsilonGsta1-1Gth1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed |
Database Links | Reactome: R-HSA-156590Reactome: R-HSA-189483Reactome: R-HSA-9748787Reactome: R-HSA-9818027 |
Cellular Localisation | Cytoplasm |
Alternative Protein Names | Glutathione S-Transferase A1 protein13-Hydroperoxyoctadecadienoate Peroxidase proteinAndrost-5-Ene-3 -17-Dione Isomerase proteinGst Ha Subunit 1 proteinGst Class-Alpha Member 1 proteinGst-Epsilon proteinGsta1-1 proteinGth1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed proteinGSTA1 protein |
Information sourced from Uniprot.org
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