| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.123ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This GRIN2D Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
GRIN2D |
| Gene ID: |
2906 |
| Uniprot ID: |
NMDE4_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. |
| Protein Name | Glutamate Receptor Ionotropic - Nmda 2dGlun2dEb11Glutamate Nmda Receptor Subunit Epsilon-4N-Methyl D-Aspartate Receptor Subtype 2dNmdar2dNr2d |
| Database Links | Reactome: R-HSA-438066Reactome: R-HSA-442982Reactome: R-HSA-5673001Reactome: R-HSA-6794361Reactome: R-HSA-8849932Reactome: R-HSA-9609736Reactome: R-HSA-9617324Reactome: R-HSA-9620244 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell Membrane |
| Alternative ELISA Names | Glutamate Receptor Ionotropic - Nmda 2d ELISA kitGlun2d ELISA kitEb11 ELISA kitGlutamate Nmda Receptor Subunit Epsilon-4 ELISA kitN-Methyl D-Aspartate Receptor Subtype 2d ELISA kitNmdar2d ELISA kitNr2d ELISA kitGRIN2D ELISA kitGluN2D ELISA kitNMDAR2D ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
