Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.061ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This GPR109B Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
HCAR3 |
Gene ID: |
8843 |
Uniprot ID: |
HCAR3_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expression largely restricted to adipose tissue and spleen. |
Post Translational Modifications | |
Function | Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. |
Protein Name | Hydroxycarboxylic Acid Receptor 3G-Protein Coupled Receptor 109bG-Protein Coupled Receptor Hm74G-Protein Coupled Receptor Hm74bNiacin Receptor 2Nicotinic Acid Receptor 2 |
Database Links | Reactome: R-HSA-3296197Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Hydroxycarboxylic Acid Receptor 3 ELISA kitG-Protein Coupled Receptor 109b ELISA kitG-Protein Coupled Receptor Hm74 ELISA kitG-Protein Coupled Receptor Hm74b ELISA kitNiacin Receptor 2 ELISA kitNicotinic Acid Receptor 2 ELISA kitHCAR3 ELISA kitGPR109B ELISA kitHCA3 ELISA kitHM74B ELISA kitNIACR2 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance