| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Glucose-6-phosphate 1-dehydrogenase/G6PD-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Supplied as a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
G6PD |
| Gene ID: |
2539 |
| Uniprot ID: |
G6PD_HUMAN |
| Immunogen Region: |
Ala2-Leu515 |
| Immunogen: |
Recombinant Human Glucose-6-phosphate 1-dehydrogenase/G6PD Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala2-Leu515) of human Glucose-6-phosphate 1-dehydrogenase/G6PD (Accession #NP_001035810.1 |
| Post Translational Modifications | Acetylated by ELP3 at Lys-403.acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403.deacetylation stimulates its enzyme activity. |
| Function | Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. |
| Protein Name | Glucose-6-Phosphate 1-DehydrogenaseG6pd |
| Database Links | Reactome: R-HSA-5628897Reactome: R-HSA-71336Reactome: R-HSA-9818028 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane Protein |
| Alternative Protein Names | Glucose-6-Phosphate 1-Dehydrogenase proteinG6pd proteinG6PD protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
