| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human FOLR2-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Endotoxin: |
Less than 1EU per Mu g by the LAL method. |
| Gene Symbol: |
FOLR2 |
| Gene ID: |
2350 |
| Uniprot ID: |
FOLR2_HUMAN |
| Immunogen Region: |
Thr17-Met228 |
| Immunogen: |
Recombinant Human FOLR2 Protein is expressed from Expi293 with His tag at the C-terminal.；It contains Thr17-Met228. |
| Post Translational Modifications | N-glycosylated. |
| Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. |
| Protein Name | Folate Receptor BetaFr-BetaFolate Receptor 2Folate Receptor - Fetal/PlacentalPlacental Folate-Binding ProteinFbp |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196757 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecreted |
| Alternative Protein Names | Folate Receptor Beta proteinFr-Beta proteinFolate Receptor 2 proteinFolate Receptor - Fetal/Placental proteinPlacental Folate-Binding Protein proteinFbp proteinFOLR2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
