| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.115ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This FMO1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
FMO1 |
| Gene ID: |
2326 |
| Uniprot ID: |
FMO1_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed mainly in fetal and adult liver. |
| Post Translational Modifications | |
| Function | Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. |
| Protein Name | Flavin-Containing Monooxygenase 1Dimethylaniline Monooxygenase N-Oxide-Forming 1Dimethylaniline Oxidase 1Fetal Hepatic Flavin-Containing Monooxygenase 1Fmo 1Trimethylamine Monooxygenase |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-217271 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative ELISA Names | Flavin-Containing Monooxygenase 1 ELISA kitDimethylaniline Monooxygenase N-Oxide-Forming 1 ELISA kitDimethylaniline Oxidase 1 ELISA kitFetal Hepatic Flavin-Containing Monooxygenase 1 ELISA kitFmo 1 ELISA kitTrimethylamine Monooxygenase ELISA kitFMO1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
