| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.114ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This FIS1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
FIS1 |
| Gene ID: |
51024 |
| Uniprot ID: |
FIS1_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Ubiquitinated by MARCHF5. |
| Function | Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event. Also mediates peroxisomal fission. May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. |
| Protein Name | Mitochondrial Fission 1 ProteinFis1 HomologHfis1Tetratricopeptide Repeat Protein 11Tpr Repeat Protein 11 |
| Database Links | Reactome: R-HSA-9603798 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane ProteinPeroxisome Membrane |
| Alternative ELISA Names | Mitochondrial Fission 1 Protein ELISA kitFis1 Homolog ELISA kitHfis1 ELISA kitTetratricopeptide Repeat Protein 11 ELISA kitTpr Repeat Protein 11 ELISA kitFIS1 ELISA kitTTC11 ELISA kitCGI-135 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
