• Human ERRFI1 (ERBB Receptor Feedback Inhibitor 1) Sandwich ELISA Kit Ready-To-Use (STJE0015085)

Human ERRFI1 (ERBB Receptor Feedback Inhibitor 1) Sandwich ELISA Kit Ready-To-Use (STJE0015085)

SKU:
STJE0015085

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 12.5pg/mL
Detection Limit: 31.2-2000pg/mL
Short Description: This ERRFI1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: ERRFI1
Gene ID: 54206
Uniprot ID: ERRFI_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Negative regulator of EGFR signaling in skin morphogenesis. Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4. Inhibits EGFR catalytic activity by interfering with its dimerization. Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4. Important for normal keratinocyte proliferation and differentiation. Plays a role in modulating the response to steroid hormones in the uterus. Required for normal response to progesterone in the uterus and for fertility. Mediates epithelial estrogen responses in the uterus by regulating ESR1 levels and activation. Important for regulation of endometrium cell proliferation. Important for normal prenatal and perinatal lung development.
Protein Name Erbb Receptor Feedback Inhibitor 1
Mitogen-Inducible Gene 6 Protein
Mig-6
Database Links
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Nucleus
Associated With The Plasma Membrane Of Basal Skin Keratinocytes
Translocates Into The Nucleus Of Differentiating Suprabasal Keratinocytes
Alternative ELISA Names Erbb Receptor Feedback Inhibitor 1 ELISA kit
Mitogen-Inducible Gene 6 Protein ELISA kit
Mig-6 ELISA kit
ERRFI1 ELISA kit
MIG6 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance