• Human ErbB3 (V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3) Sandwich ELISA Kit (STJE0008689)

Human ErbB3 (V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3) Sandwich ELISA Kit (STJE0008689)

SKU:
STJE0008689

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 32pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This ErbB3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: ERBB3
Gene ID: 2065
Uniprot ID: ERBB3_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Epithelial tissues and brain.
Post Translational Modifications Autophosphorylated. Ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase.
Function Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it.ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.
Protein Name Receptor Tyrosine-Protein Kinase Erbb-3
Proto-Oncogene-Like Protein C-Erbb-3
Tyrosine Kinase-Type Cell Surface Receptor Her3
Database Links Reactome: R-HSA-1227986 P21860-1
Reactome: R-HSA-1236394 P21860-1
Reactome: R-HSA-1250196 P21860-1
Reactome: R-HSA-1257604 P21860-1
Reactome: R-HSA-1306955 P21860-1
Reactome: R-HSA-1358803 P21860-1
Reactome: R-HSA-1963642 P21860-1
Reactome: R-HSA-2219530 P21860-1
Reactome: R-HSA-5673001 P21860-1
Reactome: R-HSA-6785631 P21860-1
Reactome: R-HSA-6811558 P21860-1
Reactome: R-HSA-8847993 P21860-1
Reactome: R-HSA-8863795 P21860-1
Reactome: R-HSA-9664565 P21860-1
Reactome: R-HSA-9665686 P21860-1
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative ELISA Names Receptor Tyrosine-Protein Kinase Erbb-3 ELISA kit
Proto-Oncogene-Like Protein C-Erbb-3 ELISA kit
Tyrosine Kinase-Type Cell Surface Receptor Her3 ELISA kit
ERBB3 ELISA kit
HER3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance