| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.056ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This ELOVL1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
ELOVL1 |
| Gene ID: |
64834 |
| Uniprot ID: |
ELOV1_HUMAN |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs. |
| Protein Name | Elongation Of Very Long Chain Fatty Acids Protein 13-Keto Acyl-Coa Synthase Elovl1Elovl Fatty Acid Elongase 1Elovl Fa Elongase 1Very Long Chain 3-Ketoacyl-Coa Synthase 1Very Long Chain 3-Oxoacyl-Coa Synthase 1 |
| Database Links | Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Elongation Of Very Long Chain Fatty Acids Protein 1 ELISA kit3-Keto Acyl-Coa Synthase Elovl1 ELISA kitElovl Fatty Acid Elongase 1 ELISA kitElovl Fa Elongase 1 ELISA kitVery Long Chain 3-Ketoacyl-Coa Synthase 1 ELISA kitVery Long Chain 3-Oxoacyl-Coa Synthase 1 ELISA kitELOVL1 ELISA kitSSC1 ELISA kitCGI-88 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
