| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
12.9pg/mL |
| Detection Limit: |
31.2-2000pg/mL |
| Short Description: |
This DUSP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
DUSP1 |
| Gene ID: |
1843 |
| Uniprot ID: |
DUS1_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. |
| Post Translational Modifications | Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. |
| Function | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle. |
| Protein Name | Dual Specificity Protein Phosphatase 1Dual Specificity Protein Phosphatase Hvh1Mitogen-Activated Protein Kinase Phosphatase 1Map Kinase Phosphatase 1Mkp-1Protein-Tyrosine Phosphatase Cl100 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-5675221 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Dual Specificity Protein Phosphatase 1 ELISA kitDual Specificity Protein Phosphatase Hvh1 ELISA kitMitogen-Activated Protein Kinase Phosphatase 1 ELISA kitMap Kinase Phosphatase 1 ELISA kitMkp-1 ELISA kitProtein-Tyrosine Phosphatase Cl100 ELISA kitDUSP1 ELISA kitCL100 ELISA kitMKP1 ELISA kitPTPN10 ELISA kitVH1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
