| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.071ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This DGAT2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
DGAT2 |
| Gene ID: |
84649 |
| Uniprot ID: |
DGAT2_HUMAN |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Predominantly expressed in liver and white adipose tissue. Expressed at lower level in mammary gland, testis and peripheral blood leukocytes. Expressed in sebaceous glands of normal skin but decreased psoriatic skin. |
| Post Translational Modifications | |
| Function | Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides. Functions also as an acyl-CoA retinol acyltransferase (ARAT). Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG). |
| Protein Name | Diacylglycerol O-Acyltransferase 2Acyl-Coa Retinol O-Fatty-AcyltransferaseAratRetinol O-Fatty-AcyltransferaseDiglyceride Acyltransferase 2 |
| Database Links | Reactome: R-HSA-1482883Reactome: R-HSA-75109 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinLipid DropletCytoplasmPerinuclear Region |
| Alternative ELISA Names | Diacylglycerol O-Acyltransferase 2 ELISA kitAcyl-Coa Retinol O-Fatty-Acyltransferase ELISA kitArat ELISA kitRetinol O-Fatty-Acyltransferase ELISA kitDiglyceride Acyltransferase 2 ELISA kitDGAT2 ELISA kitHMFN1045 ELISA kitUNQ738 ELISA kitPRO1433 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
