| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
16.47pg/mL |
| Detection Limit: |
46.8-3000pg/mL |
| Short Description: |
This DEFa3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
DEFA3 |
| Gene ID: |
1668 |
| Uniprot ID: |
DEF3_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. Possesses the ability to neutralize bacterial toxins such as B. anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Blocks also herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment. |
| Protein Name | Neutrophil Defensin 3Defensin - Alpha 3Hnp-3Hp-3Hp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2Hnp-2Hp-2Hp2 |
| Database Links | Reactome: R-HSA-1461973Reactome: R-HSA-1462054 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Neutrophil Defensin 3 ELISA kitDefensin - Alpha 3 ELISA kitHnp-3 ELISA kitHp-3 ELISA kitHp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2 ELISA kitHnp-2 ELISA kitHp-2 ELISA kitHp2 ELISA kitDEFA3 ELISA kitDEF3 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
