• Human CSF2Rb (Colony Stimulating Factor 2 Receptor Beta) Sandwich ELISA Kit (STJE0008182)

Human CSF2Rb (Colony Stimulating Factor 2 Receptor Beta) Sandwich ELISA Kit (STJE0008182)

SKU:
STJE0008182

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.061ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This CSF2Rb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CSF2RB
Gene ID: 1439
Uniprot ID: IL3RB_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications May be phosphorylated by LYN.
Function Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA. In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways. In unstimulated conditions, interacts constitutively with JAK1 and ligand binding leads to JAK1 stimulation and subsequent activation of the JAK-STAT pathway.
Protein Name Cytokine Receptor Common Subunit Beta
Cdw131
Gm-Csf/Il-3/Il-5 Receptor Common Beta Subunit
Cd Antigen Cd131
Database Links Reactome: R-HSA-512988
Reactome: R-HSA-5673001
Reactome: R-HSA-5683826
Reactome: R-HSA-5688849
Reactome: R-HSA-5688890
Reactome: R-HSA-912526
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Cytokine Receptor Common Subunit Beta ELISA kit
Cdw131 ELISA kit
Gm-Csf/Il-3/Il-5 Receptor Common Beta Subunit ELISA kit
Cd Antigen Cd131 ELISA kit
CSF2RB ELISA kit
IL3RB ELISA kit
IL5RB ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance