• Human CRNN (Cornulin) Sandwich ELISA Kit Ready-To-Use (STJE0014535)

Human CRNN (Cornulin) Sandwich ELISA Kit Ready-To-Use (STJE0014535)

SKU:
STJE0014535

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.123ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This CRNN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CRNN
Gene ID: 49860
Uniprot ID: CRNN_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in the basal skin layer (at protein level). Squamous epithelia cell-specific. Expressed in the esophagus (periphery of the cells of the granular and the upper spinous layers), foreskin (granular and lower cornified cells), scalp skin (granular layer), inner root sheath of the hair follicle and in primary keratinocytes (at protein level). Expressed in the squamous epithelium of the cervix, esophagus, foreskin and larynx. Expressed in the fetal bladder and scalp skin. Expressed at very low levels in the lung, kidney, uterus, skeletal muscle, heart and fetal brain. Undetectable or barely detectable in esophageal and oral squamous cell carcinoma compared with the matched adjacent normal esophageal mucosa. Undetectable or barely detectable in larynx and esophagus from patients with pH-documented laryngopharyngeal reflux (LPR).
Post Translational Modifications
Function Promotes cell proliferation, G1/S cell cycle progression and induces expression of the cell cycle regulator CCND1. Regulates proliferation induced by pro-inflammatory cytokine response via activation of NFKB1 and PI3K/AKT signaling pathways.
Protein Name Cornulin
53 Kda Putative Calcium-Binding Protein
53 Kda Squamous Epithelial-Induced Stress Protein
58 Kda Heat Shock Protein
Squamous Epithelial Heat Shock Protein 53
Tumor-Related Protein
Database Links
Cellular Localisation Cytoplasm
Does Not Colocalize With Tgm1
Alternative ELISA Names Cornulin ELISA kit
53 Kda Putative Calcium-Binding Protein ELISA kit
53 Kda Squamous Epithelial-Induced Stress Protein ELISA kit
58 Kda Heat Shock Protein ELISA kit
Squamous Epithelial Heat Shock Protein 53 ELISA kit
Tumor-Related Protein ELISA kit
CRNN ELISA kit
C1orf10 ELISA kit
DRC1 ELISA kit
PDRC1 ELISA kit
SEP53 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance