| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.129ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This CPSF1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
CPSF1 |
| Gene ID: |
29894 |
| Uniprot ID: |
CPSF1_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Widely expressed, with high expression in the retina. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain. |
| Protein Name | Cleavage And Polyadenylation Specificity Factor Subunit 1Cleavage And Polyadenylation Specificity Factor 160 Kda SubunitCpsf 160 Kda Subunit |
| Database Links | Reactome: R-HSA-159231Reactome: R-HSA-6784531Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | NucleusNucleoplasm |
| Alternative ELISA Names | Cleavage And Polyadenylation Specificity Factor Subunit 1 ELISA kitCleavage And Polyadenylation Specificity Factor 160 Kda Subunit ELISA kitCpsf 160 Kda Subunit ELISA kitCPSF1 ELISA kitCPSF160 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
