Function | Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain.the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation. |
Protein Name | Bifunctional Coenzyme A SynthaseCoa SynthaseNbpPov-2 Includes - Phosphopantetheine AdenylyltransferaseDephospho-Coa PyrophosphorylasePantetheine-Phosphate AdenylyltransferasePpat - Dephospho-Coa KinaseDpckDephosphocoenzyme A KinaseDpcoak |
Database Links | Reactome: R-HSA-196783 |
Cellular Localisation | CytoplasmMitochondrion MatrixThe Protein Is Mainly Present In The Mitochondrial MatrixProbably Anchored To The Inner Mitochondrial MembraneBut Is Also Present In Cell Lysate |
Alternative Protein Names | Bifunctional Coenzyme A Synthase proteinCoa Synthase proteinNbp proteinPov-2 Includes - Phosphopantetheine Adenylyltransferase proteinDephospho-Coa Pyrophosphorylase proteinPantetheine-Phosphate Adenylyltransferase proteinPpat - Dephospho-Coa Kinase proteinDpck proteinDephosphocoenzyme A Kinase proteinDpcoak proteinCOASY proteinPSEC0106 protein |
Information sourced from Uniprot.org