Human COASY protein (Recombinant) (N-His) (STJP005281)

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STJP005281
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human COASY-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: COASY
Gene ID: 80347
Uniprot ID: COASY_HUMAN
Immunogen Region: Pro101-Ile366
Immunogen: Homo sapiens (Human)
Function Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain.the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation.
Protein Name Bifunctional Coenzyme A Synthase
Coa Synthase
Nbp
Pov-2 Includes - Phosphopantetheine Adenylyltransferase
Dephospho-Coa Pyrophosphorylase
Pantetheine-Phosphate Adenylyltransferase
Ppat - Dephospho-Coa Kinase
Dpck
Dephosphocoenzyme A Kinase
Dpcoak
Database Links Reactome: R-HSA-196783
Cellular Localisation Cytoplasm
Mitochondrion Matrix
The Protein Is Mainly Present In The Mitochondrial Matrix
Probably Anchored To The Inner Mitochondrial Membrane
But Is Also Present In Cell Lysate
Alternative Protein Names Bifunctional Coenzyme A Synthase protein
Coa Synthase protein
Nbp protein
Pov-2 Includes - Phosphopantetheine Adenylyltransferase protein
Dephospho-Coa Pyrophosphorylase protein
Pantetheine-Phosphate Adenylyltransferase protein
Ppat - Dephospho-Coa Kinase protein
Dpck protein
Dephosphocoenzyme A Kinase protein
Dpcoak protein
COASY protein
PSEC0106 protein

Information sourced from Uniprot.org