| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human CFHR2-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of 20mM PB, 200mM NaCl, 2mM EDTA, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CFHR2 |
| Gene ID: |
3080 |
| Uniprot ID: |
FHR2_HUMAN |
| Immunogen Region: |
Glu19-Lys270 |
| Immunogen: |
Recombinant Human CFHR2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu19-Lys270) of human CFHR2 (Accession #NP_001299601.1) fused with a 6×His tag at the C-terminus. |
| Post Translational Modifications | N-glycosylated. |
| Function | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. |
| Protein Name | Complement Factor H-Related Protein 2Fhr-2Ddesk59H Factor-Like 3H Factor-Like Protein 2 |
| Database Links | Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Complement Factor H-Related Protein 2 proteinFhr-2 proteinDdesk59 proteinH Factor-Like 3 proteinH Factor-Like Protein 2 proteinCFHR2 proteinCFHL2 proteinFHR2 proteinHFL3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
