| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CD339/JAG1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | JAG1 |
| Gene ID: | 182 |
| Uniprot ID: | JAG1_HUMAN |
| Immunogen Region: | Gly33-Asp250 |
| Immunogen: | Homo sapiens (Human) |
| Function | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). |
| Protein Name | Protein Jagged-1Jagged1Hj1Cd Antigen Cd339 |
| Database Links | Reactome: R-HSA-2122948Reactome: R-HSA-2644606Reactome: R-HSA-2660826Reactome: R-HSA-2691232Reactome: R-HSA-2894862Reactome: R-HSA-2979096Reactome: R-HSA-8941856Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9013507Reactome: R-HSA-9013700Reactome: R-HSA-9831926 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Protein Names | Protein Jagged-1 proteinJagged1 proteinHj1 proteinCd Antigen Cd339 proteinJAG1 proteinJAGL1 protein |
Information sourced from Uniprot.org