Post Translational Modifications | Mono-ubiquitinated. Proteolytically cleaved in late endosomes to yield a soluble form. |
Function | T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active. |
Protein Name | T-Cell Surface Glycoprotein Cd1e - Membrane-AssociatedHcd1eR2g1Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - SolubleScd1e |
Cellular Localisation | T-Cell Surface Glycoprotein Cd1eMembrane-Associated: Golgi Apparatus MembraneSingle-Pass Type I Membrane ProteinEarly EndosomeLate EndosomePredominantly Localized In The Trans-Golgi Network In Immature Dendritic CellsAnd As A CleavedSoluble Protein In The Lysosome Lumen Of Mature Dendritic CellsSoluble: Lysosome Lumen |
Alternative Protein Names | T-Cell Surface Glycoprotein Cd1e - Membrane-Associated proteinHcd1e proteinR2g1 proteinCd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - Soluble proteinScd1e proteinCD1E protein |
Information sourced from Uniprot.org