Human CD158k/KIR3DL2 protein (Recombinant) (C-Fc) (STJP006623)

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STJP006623
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD158k/KIR3DL2-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: KIR3DL2
Gene ID: 3812
Uniprot ID: KI3L2_HUMAN
Immunogen Region: Met1-His338
Immunogen: Homo sapiens (Human)
Function Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity.
Protein Name Killer Cell Immunoglobulin-Like Receptor 3dl2
Cd158 Antigen-Like Family Member K
Natural Killer-Associated Transcript 4
Nkat-4
P70 Natural Killer Cell Receptor Clone Cl-5
P70 Nk Receptor Cl-5
Cd Antigen Cd158k
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Killer Cell Immunoglobulin-Like Receptor 3dl2 protein
Cd158 Antigen-Like Family Member K protein
Natural Killer-Associated Transcript 4 protein
Nkat-4 protein
P70 Natural Killer Cell Receptor Clone Cl-5 protein
P70 Nk Receptor Cl-5 protein
Cd Antigen Cd158k protein
KIR3DL2 protein
CD158K protein
NKAT4 protein

Information sourced from Uniprot.org