| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human CCL8/MCP-2-N-hFC protein was developed from hek293 cells and has a target region of N-hFC. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCL8 |
| Gene ID: |
6355 |
| Uniprot ID: |
CCL8_HUMAN |
| Immunogen Region: |
Gln24-Pro99 |
| Immunogen: |
Recombinant Human CCL8/MCP-2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln24-Pro99) of human CCL8/MCP-2 (Accession #NP_005614.2) fused with and a hFc tag at the N-terminus. |
| Post Translational Modifications | N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. |
| Protein Name | C-C Motif Chemokine 8Hc14Monocyte Chemoattractant Protein 2Monocyte Chemotactic Protein 2Mcp-2Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 8 proteinHc14 proteinMonocyte Chemoattractant Protein 2 proteinMonocyte Chemotactic Protein 2 proteinMcp-2 proteinSmall-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 proteinCCL8 proteinMCP2 proteinSCYA10 proteinSCYA8 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
