Human CCL22/MDC protein (Recombinant) (N-GST) (STJP003169)

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STJP003169
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL22/MDC-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CCL22
Gene ID: 6367
Uniprot ID: CCL22_HUMAN
Immunogen Region: Gly25-Gln93
Immunogen: Homo sapiens (Human)
Post Translational Modifications The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.
Function May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
Protein Name C-C Motif Chemokine 22
Cc Chemokine Stcp-1
Mdc(1-69
Macrophage-Derived Chemokine
Small-Inducible Cytokine A22
Stimulated T-Cell Chemotactic Protein 1 Cleaved Into - Mdc(3-69 - Mdc(5-69 - Mdc(7-69
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 22 protein
Cc Chemokine Stcp-1 protein
Mdc(1-69 protein
Macrophage-Derived Chemokine protein
Small-Inducible Cytokine A22 protein
Stimulated T-Cell Chemotactic Protein 1 Cleaved Into - Mdc(3-69 - Mdc(5-69 - Mdc(7-69 protein
CCL22 protein
MDC protein
SCYA22 protein
A-152E5.1 protein

Information sourced from Uniprot.org

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