Human CCL21/6Ckine protein (Recombinant) (N-His) (STJP003164)

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STJP003164
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL21/6Ckine-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CCL21
Gene ID: 6366
Uniprot ID: CCL21_HUMAN
Immunogen Region: Ser24-Pro134
Immunogen: Homo sapiens (Human)
Function Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name C-C Motif Chemokine 21
6ckine
Beta-Chemokine Exodus-2
Secondary Lymphoid-Tissue Chemokine
Slc
Small-Inducible Cytokine A21
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 21 protein
6ckine protein
Beta-Chemokine Exodus-2 protein
Secondary Lymphoid-Tissue Chemokine protein
Slc protein
Small-Inducible Cytokine A21 protein
CCL21 protein
SCYA21 protein
UNQ784 protein
PRO1600 protein

Information sourced from Uniprot.org

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