Human CCL15/HCC-2/LKN-1/MIP-5 protein (Recombinant) (N-GST) (STJP005508)

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STJP005508
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL15/HCC-2/LKN-1/MIP-5-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CCL15
Gene ID: 6359
Uniprot ID: CCL15_HUMAN
Immunogen Region: Ser46-Ile113
Immunogen: Homo sapiens (Human)
Post Translational Modifications The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms CCL15(22-92), CCL15(25-92) and CCL15(29-92) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro.
Function Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the CCL15.
Protein Name C-C Motif Chemokine 15
Chemokine Cc-2
Hcc-2
Leukotactin-1
Lkn-1
Mip-1 Delta
Macrophage Inflammatory Protein 5
Mip-5
Mrp-2b
Ncc-3
Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 15 protein
Chemokine Cc-2 protein
Hcc-2 protein
Leukotactin-1 protein
Lkn-1 protein
Mip-1 Delta protein
Macrophage Inflammatory Protein 5 protein
Mip-5 protein
Mrp-2b protein
Ncc-3 protein
Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92 protein
CCL15 protein
MIP5 protein
NCC3 protein
SCYA15 protein

Information sourced from Uniprot.org

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