• Human CAPZb (Capping Protein Muscle Z Line Beta) Sandwich ELISA Kit (STJE0007678)

Human CAPZb (Capping Protein Muscle Z Line Beta) Sandwich ELISA Kit (STJE0007678)

SKU:
STJE0007678

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.052ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This CAPZb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CAPZB
Gene ID: 832
Uniprot ID: CAPZB_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules.
Protein Name F-Actin-Capping Protein Subunit Beta
Capz Beta
Database Links Reactome: R-HSA-2132295
Reactome: R-HSA-3371497
Reactome: R-HSA-6807878
Reactome: R-HSA-6811436
Reactome: R-HSA-9013405
Reactome: R-HSA-9035034
Reactome: R-HSA-9662360
Reactome: R-HSA-983231
Cellular Localisation Cytoplasm
Cytoskeleton
Myofibril
Sarcomere
Alternative ELISA Names F-Actin-Capping Protein Subunit Beta ELISA kit
Capz Beta ELISA kit
CAPZB ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance