| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human B7-H2/ICOSLG/CD275-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications. |
| Conjugation: |
Biotin |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Endotoxin: |
Less than 1EU per Mu g by the LAL method. |
| Gene Symbol: |
ICOSLG |
| Gene ID: |
23308 |
| Uniprot ID: |
ICOSL_HUMAN |
| Immunogen Region: |
Asp19-Ser258 |
| Immunogen: |
Recombinant Biotinylated Human B7-H2/ICOSLG Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.；It contains Asp19-Ser258. |
| Function | Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion.induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. |
| Protein Name | Icos LigandB7 Homolog 2B7-H2B7-Like Protein Gl50B7-Related Protein 1B7rp-1Cd Antigen Cd275 |
| Database Links | Reactome: R-HSA-388841 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Icos Ligand proteinB7 Homolog 2 proteinB7-H2 proteinB7-Like Protein Gl50 proteinB7-Related Protein 1 proteinB7rp-1 proteinCd Antigen Cd275 proteinICOSLG proteinB7H2 proteinB7RP1 proteinICOSL proteinKIAA0653 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
