| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.057ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This ASPH Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
ASPH |
| Gene ID: |
444 |
| Uniprot ID: |
ASPH_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Isoform 1 is detected in all tissues tested. Isoform 8 is mainly expressed in pancreas, heart, brain, kidney and liver. Isoform 8 is expressed in kidney (at protein level). |
| Post Translational Modifications | |
| Function | Isoform 1: Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins. Isoform 8: Membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells. |
| Protein Name | Aspartyl/Asparaginyl Beta-HydroxylaseAspartate Beta-HydroxylaseAsp Beta-HydroxylasePeptide-Aspartate Beta-Dioxygenase |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-5578775 |
| Cellular Localisation | Isoform 1: Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinIsoform 4: Sarcoplasmic Reticulum MembraneIsoform 8: Endoplasmic Reticulum Membrane |
| Alternative ELISA Names | Aspartyl/Asparaginyl Beta-Hydroxylase ELISA kitAspartate Beta-Hydroxylase ELISA kitAsp Beta-Hydroxylase ELISA kitPeptide-Aspartate Beta-Dioxygenase ELISA kitASPH ELISA kitBAH ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
