| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.126ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This AEBP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
AEBP1 |
| Gene ID: |
165 |
| Uniprot ID: |
AEBP1_HUMAN |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Expressed in osteoblast and visceral fat. |
| Post Translational Modifications | Phosphorylated by MAPK1 in vitro. |
| Function | Isoform 1: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix. Isoform 2: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. |
| Protein Name | Adipocyte Enhancer-Binding Protein 1Ae-Binding Protein 1Aortic Carboxypeptidase-Like Protein |
| Database Links | |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmNucleus |
| Alternative ELISA Names | Adipocyte Enhancer-Binding Protein 1 ELISA kitAe-Binding Protein 1 ELISA kitAortic Carboxypeptidase-Like Protein ELISA kitAEBP1 ELISA kitACLP ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
