• Human ACAT1 (Acetyl Coenzyme A Acetyltransferase 1) Sandwich ELISA Kit (STJE0006834)

Human ACAT1 (Acetyl Coenzyme A Acetyltransferase 1) Sandwich ELISA Kit (STJE0006834)

SKU:
STJE0006834

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 4.75pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description: This ACAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: ACAT1
Gene ID: 38
Uniprot ID: THIL_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Succinylation at Lys-268, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5.
Function This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism.
Protein Name Acetyl-Coa Acetyltransferase - Mitochondrial
Acetoacetyl-Coa Thiolase
T2
Database Links Reactome: R-HSA-70895
Reactome: R-HSA-77108
Reactome: R-HSA-77111
Cellular Localisation Mitochondrion
Alternative ELISA Names Acetyl-Coa Acetyltransferase - Mitochondrial ELISA kit
Acetoacetyl-Coa Thiolase ELISA kit
T2 ELISA kit
ACAT1 ELISA kit
ACAT ELISA kit
MAT ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance